What Makes a Good Target?
This interactive workshop will equip you with the core skills and understanding in critical areas of what makes a good
ADC target. Covering essential elements in ADC target discovery and early development, this workshop will enable you to:
• Understand the impact of conjugation site selection on your ADC
• Choose the optimum “antibody” format
• Select the most appropriate ADC target which is easily accessible
• Learn about cellular assays
Target Selection & Methods to Mitigate ON-Target/OFF-Tumor Toxicity
This workshop will review in detail target selection criteria and processes. We will discuss properties that are critical
for maximizing ADC efficacy, resources for the target identification process, and evaluate some successes and
failures of ADC programs from the point of view of target selection.
We will also discuss ways to approach drugging non-ideal targets, particularly due to high normal healthy tissue expression, and methods such as protease-activatable prodrug ADCs that can convert undruggable targets to ones having a viable therapeutic index.
CEO & Founder
Sr Vice President