Tumor-Specific Epitopes (TSEs) for Antibody Recognition of Misfolded Proteins
Time: 12:15 pm
day: Conference Day One
Details:
- Discussing how misfolding specific epitopes allow for discrimination of antibody neutralization of neurodegenerative pathogenic proteins from physiologically functional isoforms
- Reviewing how cell surface proteins misfold on tumor cells from aberrant cell biology and tumor bed abnormalities
- Unveiling how computational identification of TSEs permit generation of cancer-selective antibodies and ADCs with decreased on-target toxicity, enabling more powerful payloads