Roundtable Discussion: Highlighting the Importance of Target Antigen Biology as a Key Driver of ADC Success
Time: 12:45 pm
day: Conference Day Two
Details:
- Focusing the antigen as a functional target vs. payload delivery route to establish an allencompassing target selection strategy
- Questioning whether antigen density (sites per cell) is an important parameter? Is rapid internalization essential?
- How to select the best epitope / domain for ADC binding? Should immune effector potential (ADCC, ADCP) be strongly considered?