More than the Sum of Their Parts: Integrating Data & Knowledge of ADCs in a QSP Platform Model to Predict Efficacy & Toxicity
Time: 1:45 pm
day: Conference Day One
Details:
- We have made substantial progress towards developing a quantitative systems pharmacology platform model for ADC to predict ADC efficacy and hematological toxicities
- We demonstrated that we can predict clinical outcome for two ADC molecules
- The QSP platform model can be applied early on to help with target selection and predicting optimal drug properties
