Identification of Novel pHLA Targets for Solid Tumor Targeting with ADCs

Time: 10:00 am
day: Day Two


  • Discuss the advantages of intracellular targets (pHLAs) versus viral, neoantigens or conventional cell surface antigens
  • Uncover strategies to find the most prevalent and immunogenic pHLA targets in tumors from CPI responders
  • Review the selection of ADCs targeting pHLA targets to avoid off-tumor, on-target toxicities in normal tissues