Designing Site-Specific ADCs to Maximize Target-Mediated Payload Delivery

Time: 11:30 am
day: Day Two


  • Outlining HT identification of bioconjugation site from ADC libraries
  • Discovering glycosylated variants amenable to bTGase conjugation
  • Discussing characterization of thermal and metabolic stabilities of site-specific ADCs to guide construct design for maximizing target-dependent delivery