Designing Site-Specific ADCs to Maximize Target-Mediated Payload Delivery
Time: 12:10 pm
day: Day Two
Details:
- Outlining HT identification of bioconjugation site from ADC libraries
- Discovering glycosylated variants amenable to bTGase conjugation
- Discussing characterization of thermal and metabolic stabilities of site-specific ADCs to guide construct design for maximizing target-dependent delivery
