A Critical Appraisal of Target Mediated & On-Target/Off-Tumor Toxicities of ADCs

Time: 11:00 am
day: Day Two


  • Understanding the critical importance of target expression and biology in maximizing the therapeutic index
  • Discussing the challenges of predicting on target toxicities based on target expression on normal tissues
  • Outlining the importance of the antibody quality, payload potency, linker and conjugation on target medicated toxicities